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Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation

Hepatitis B virus (HBV) delivers a partially double-stranded, relaxed circular (RC) DNA genome in complete virions to the host cell nucleus for conversion to the covalently closed circular (CCC) DNA, which establishes and sustains viral infection. An overlength pregenomic RNA (pgRNA) is then transcr...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Xi, Ji, Gao, Lu, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145273/
https://www.ncbi.nlm.nih.gov/pubmed/32226051
http://dx.doi.org/10.1371/journal.ppat.1008459