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Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein–Ligand Interaction Studies

[Image: see text] In modern biochemistry, protein stability and ligand interactions are of high interest. These properties are often studied with methods requiring labeled biomolecules, as the existing methods utilizing luminescent external probes suffer from low sensitivity. Currently available lab...

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Detalles Bibliográficos
Autores principales: Vuorinen, Emmiliisa, Valtonen, Salla, Eskonen, Ville, Kariniemi, Taru, Jakovleva, Jelena, Kopra, Kari, Härmä, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145280/
https://www.ncbi.nlm.nih.gov/pubmed/32013400
http://dx.doi.org/10.1021/acs.analchem.9b05712