Chitosan Oligosaccharides Attenuate Amyloid Formation of hIAPP and Protect Pancreatic β-Cells from Cytotoxicity

The deposition of aggregated human islet amyloid polypeptide (hIAPP) in the pancreas, that has been associated with β-cell dysfunction, is one of the common pathological features of patients with type 2 diabetes (T2D). Therefore, hIAPP aggregation inhibitors hold a promising therapeutic schedule for...

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Detalles Bibliográficos
Autores principales: Meng, Qin-Yu, Wang, Hua, Cui, Zi-Bo, Yu, Wen-Gong, Lu, Xin-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145300/
https://www.ncbi.nlm.nih.gov/pubmed/32183067
http://dx.doi.org/10.3390/molecules25061314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145300/
https://www.ncbi.nlm.nih.gov/pubmed/32183067
http://dx.doi.org/10.3390/molecules25061314

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