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Upregulation of microRNA-204 improves insulin resistance of polycystic ovarian syndrome via inhibition of HMGB1 and the inactivation of the TLR4/NF-κB pathway

There is growing evidence of the position of microRNAs (miRs) in polycystic ovarian syndrome (PCOS), thus our objective was to discuss the impact of miR-204 on insulin resistance (IR) in PCOS by targeting highmobility group box protein 1(HMGB1)-mediated toll-like receptor 4(TLR4)/nuclear factor-kapp...

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Detalles Bibliográficos
Autores principales: Jiang, Bin, Xue, Min, Xu, Dabao, Song, Yujia, Zhu, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145337/
https://www.ncbi.nlm.nih.gov/pubmed/32089069
http://dx.doi.org/10.1080/15384101.2020.1724601