Modular Synthesis of Polycyclic Alkaloid Scaffolds via an Enantioselective Dearomative Cascade

[Image: see text] The polycyclic core of the akuammiline alkaloids can be synthesized from simple tryptamine and tryptophol derivatives via a Ag(I)-catalyzed enantioselective dearomative cyclization cascade sequence. The complex tetracyclic scaffolds are prepared via a rapid, versatile, three-step m...

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Detalles Bibliográficos
Autores principales: Rossi-Ashton, James A., Clarke, Aimee K., Taylor, Richard J. K., Unsworth, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145359/
https://www.ncbi.nlm.nih.gov/pubmed/31940208
http://dx.doi.org/10.1021/acs.orglett.0c00053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145359/
https://www.ncbi.nlm.nih.gov/pubmed/31940208
http://dx.doi.org/10.1021/acs.orglett.0c00053

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