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Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

[Image: see text] The distinction between surface and bulk crystallization of amorphous pharmaceuticals, as well as the importance of surface crystallization for pharmaceutical performance, is becoming increasingly evident. An emerging strategy in stabilizing the amorphous drug form is to utilize th...

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Detalles Bibliográficos
Autores principales: Novakovic, Dunja, Peltonen, Leena, Isomäki, Antti, Fraser-Miller, Sara J., Nielsen, Line Hagner, Laaksonen, Timo, Strachan, Clare J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145361/
https://www.ncbi.nlm.nih.gov/pubmed/32027513
http://dx.doi.org/10.1021/acs.molpharmaceut.9b01263