TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8(+) T Cell Activation Setpoint

The ability of T cells to sense and respond to environmental cues by altering their functional capabilities is critical for a safe and optimally protective immune response. One of the important properties that contributes to this goal is the activation set-point of the T cell. Here we report a new p...

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Detalles Bibliográficos
Autores principales: Crofts, Kali F., Holbrook, Beth C., Soto-Pantoja, David R., Ornelles, David A., Alexander-Miller, Martha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145404/
https://www.ncbi.nlm.nih.gov/pubmed/32300344
http://dx.doi.org/10.3389/fimmu.2020.00540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145404/
https://www.ncbi.nlm.nih.gov/pubmed/32300344
http://dx.doi.org/10.3389/fimmu.2020.00540

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