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TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8(+) T Cell Activation Setpoint
The ability of T cells to sense and respond to environmental cues by altering their functional capabilities is critical for a safe and optimally protective immune response. One of the important properties that contributes to this goal is the activation set-point of the T cell. Here we report a new p...
Autores principales: | Crofts, Kali F., Holbrook, Beth C., Soto-Pantoja, David R., Ornelles, David A., Alexander-Miller, Martha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145404/ https://www.ncbi.nlm.nih.gov/pubmed/32300344 http://dx.doi.org/10.3389/fimmu.2020.00540 |
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