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DNA Methylation and Type 2 Diabetes: the Use of Mendelian Randomization to Assess Causality

PURPOSE OF REVIEW: This review summarises recent advances in the field of epigenetics in order to understand the aetiology of type 2 diabetes (T2D). RECENT FINDINGS: DNA methylation at a number of loci has been shown to be robustly associated with T2D, including TXNIP, ABCG1, CPT1A, and SREBF1. Howe...

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Detalles Bibliográficos
Autores principales: Juvinao-Quintero, Diana L., Hivert, Marie-France, Sharp, Gemma C., Relton, Caroline L., Elliott, Hannah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145450/
https://www.ncbi.nlm.nih.gov/pubmed/32274260
http://dx.doi.org/10.1007/s40142-019-00176-5