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Are the intrinsically disordered linkers involved in SSB binding to accessory proteins?

Escherichia coli single strand (ss) DNA binding (SSB) protein protects ssDNA intermediates and recruits at least 17 SSB interacting proteins (SIPs) during genome maintenance. The SSB C-termini contain a 9 residue acidic tip and a 56 residue intrinsically disordered linker (IDL). The acidic tip inter...

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Detalles Bibliográficos
Autores principales: Shinn, Min Kyung, Kozlov, Alexander G, Nguyen, Binh, Bujalowski, Wlodek M, Lohman, Timothy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145534/
https://www.ncbi.nlm.nih.gov/pubmed/31329947
http://dx.doi.org/10.1093/nar/gkz606