A general strategy exploiting m(5)C duplex-remodelling effect for selective detection of RNA and DNA m(5)C methyltransferase activity in cells

RNA:5-methylcytosine (m(5)C) methyltransferases are currently the focus of intense research following a series of high-profile reports documenting their physiological links to several diseases. However, no methods exist which permit the specific analysis of RNA:m(5)C methyltransferases in cells. Her...

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Detalles Bibliográficos
Autores principales: Yang, Tianming, Low, Joanne J A, Woon, Esther C Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145549/
https://www.ncbi.nlm.nih.gov/pubmed/31691820
http://dx.doi.org/10.1093/nar/gkz1047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145549/
https://www.ncbi.nlm.nih.gov/pubmed/31691820
http://dx.doi.org/10.1093/nar/gkz1047

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