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A general strategy exploiting m(5)C duplex-remodelling effect for selective detection of RNA and DNA m(5)C methyltransferase activity in cells
RNA:5-methylcytosine (m(5)C) methyltransferases are currently the focus of intense research following a series of high-profile reports documenting their physiological links to several diseases. However, no methods exist which permit the specific analysis of RNA:m(5)C methyltransferases in cells. Her...
Autores principales: | Yang, Tianming, Low, Joanne J A, Woon, Esther C Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145549/ https://www.ncbi.nlm.nih.gov/pubmed/31691820 http://dx.doi.org/10.1093/nar/gkz1047 |
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