Structural transitions in the RNA 7SK 5′ hairpin and their effect on HEXIM binding

7SK RNA, as part of the 7SK ribonucleoprotein complex, is crucial to the regulation of transcription by RNA-polymerase II, via its interaction with the positive transcription elongation factor P-TEFb. The interaction is induced by binding of the protein HEXIM to the 5′ hairpin (HP1) of 7SK RNA. Four...

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Detalles Bibliográficos
Autores principales: Röder, Konstantin, Stirnemann, Guillaume, Dock-Bregeon, Anne-Catherine, Wales, David J, Pasquali, Samuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein Complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145557/
https://www.ncbi.nlm.nih.gov/pubmed/31732748
http://dx.doi.org/10.1093/nar/gkz1071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145557/
https://www.ncbi.nlm.nih.gov/pubmed/31732748
http://dx.doi.org/10.1093/nar/gkz1071

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