A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N(6)-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription

Rediscovered as a potential eukaryotic epigenetic mark, DNA N(6)-adenine methylation (6mA) varies across species in abundance and its relationships with transcription. Here we characterize AMT1—representing a distinct MT-A70 family methyltransferase—in the ciliate Tetrahymena thermophila. AMT1 loss-...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Sheng, Yalan, Liu, Yongqiang, Zhang, Wenxin, Cheng, Ting, Duan, Lili, Pan, Bo, Qiao, Yu, Liu, Yifan, Gao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145601/
https://www.ncbi.nlm.nih.gov/pubmed/31722409
http://dx.doi.org/10.1093/nar/gkz1053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145601/
https://www.ncbi.nlm.nih.gov/pubmed/31722409
http://dx.doi.org/10.1093/nar/gkz1053

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