Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

Modifications of ribosomal RNA expand the nucleotide repertoire and thereby contribute to ribosome heterogeneity and translational regulation of gene expression. One particular m(5)C modification of 25S ribosomal RNA, which is introduced by Rcm1p, was previously shown to modulate stress responses an...

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Detalles Bibliográficos
Autores principales: Heissenberger, Clemens, Liendl, Lisa, Nagelreiter, Fabian, Gonskikh, Yulia, Yang, Guohuan, Stelzer, Elena M, Krammer, Teresa L, Micutkova, Lucia, Vogt, Stefan, Kreil, David P, Sekot, Gerhard, Siena, Emilio, Poser, Ina, Harreither, Eva, Linder, Angela, Ehret, Viktoria, Helbich, Thomas H, Grillari-Voglauer, Regina, Jansen-Dürr, Pidder, Koš, Martin, Polacek, Norbert, Grillari, Johannes, Schosserer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145617/
https://www.ncbi.nlm.nih.gov/pubmed/31722427
http://dx.doi.org/10.1093/nar/gkz1043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145617/
https://www.ncbi.nlm.nih.gov/pubmed/31722427
http://dx.doi.org/10.1093/nar/gkz1043

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