An improved platform for functional assessment of large protein libraries in mammalian cells

Multiplex genetic assays can simultaneously test thousands of genetic variants for a property of interest. However, limitations of existing multiplex assay methods in cultured mammalian cells hinder the breadth, speed and scale of these experiments. Here, we describe a series of improvements that gr...

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Detalles Bibliográficos
Autores principales: Matreyek, Kenneth A, Stephany, Jason J, Chiasson, Melissa A, Hasle, Nicholas, Fowler, Douglas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145622/
https://www.ncbi.nlm.nih.gov/pubmed/31612958
http://dx.doi.org/10.1093/nar/gkz910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145622/
https://www.ncbi.nlm.nih.gov/pubmed/31612958
http://dx.doi.org/10.1093/nar/gkz910

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