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Causal Inference Engine: a platform for directional gene set enrichment analysis and inference of active transcriptional regulators

Inference of active regulatory mechanisms underlying specific molecular and environmental perturbations is essential for understanding cellular response. The success of inference algorithms relies on the quality and coverage of the underlying network of regulator–gene interactions. Several commercia...

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Detalles Bibliográficos
Autores principales: Farahmand, Saman, O’Connor, Corey, Macoska, Jill A, Zarringhalam, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145661/
https://www.ncbi.nlm.nih.gov/pubmed/31701125
http://dx.doi.org/10.1093/nar/gkz1046