Polynucleotide phosphorylase promotes the stability and function of Hfq-binding sRNAs by degrading target mRNA-derived fragments

In many Gram-negative and some Gram-positive bacteria, small regulatory RNAs (sRNAs) that bind the RNA chaperone Hfq have a pivotal role in modulating virulence, stress responses, metabolism and biofilm formation. These sRNAs recognize transcripts through base-pairing, and sRNA–mRNA annealing conseq...

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Detalles Bibliográficos
Autores principales: Cameron, Todd A, Matz, Lisa M, Sinha, Dhriti, De Lay, Nicholas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145675/
https://www.ncbi.nlm.nih.gov/pubmed/31329973
http://dx.doi.org/10.1093/nar/gkz616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145675/
https://www.ncbi.nlm.nih.gov/pubmed/31329973
http://dx.doi.org/10.1093/nar/gkz616

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