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FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis
During meiosis, telomere attachment to the inner nuclear envelope is required for proper pairing of homologous chromosomes and recombination. Here, we identified F-box protein 47 (FBXO47) as a regulator of the telomeric shelterin complex that is specifically expressed during meiotic prophase I. Knoc...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145685/ https://www.ncbi.nlm.nih.gov/pubmed/31724724 http://dx.doi.org/10.1093/nar/gkz992 |