FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis

During meiosis, telomere attachment to the inner nuclear envelope is required for proper pairing of homologous chromosomes and recombination. Here, we identified F-box protein 47 (FBXO47) as a regulator of the telomeric shelterin complex that is specifically expressed during meiotic prophase I. Knoc...

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Detalles Bibliográficos
Autores principales: Hua, Rong, Wei, Huafang, Liu, Chao, Zhang, Yue, Liu, Siyu, Guo, Yueshuai, Cui, Yiqiang, Zhang, Xin, Guo, Xuejiang, Li, Wei, Liu, Mingxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145685/
https://www.ncbi.nlm.nih.gov/pubmed/31724724
http://dx.doi.org/10.1093/nar/gkz992

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