The FMRP–MOV10 complex: a translational regulatory switch modulated by G-Quadruplexes

The Fragile X Mental Retardation Protein (FMRP) is an RNA binding protein that regulates translation and is required for normal cognition. FMRP upregulates and downregulates the activity of microRNA (miRNA)-mediated silencing in the 3′ UTR of a subset of mRNAs through its interaction with RNA helica...

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Detalles Bibliográficos
Autores principales: Kenny, Phillip J, Kim, Miri, Skariah, Geena, Nielsen, Joshua, Lannom, Monica C, Ceman, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145700/
https://www.ncbi.nlm.nih.gov/pubmed/31740951
http://dx.doi.org/10.1093/nar/gkz1092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145700/
https://www.ncbi.nlm.nih.gov/pubmed/31740951
http://dx.doi.org/10.1093/nar/gkz1092

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