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The FMRP–MOV10 complex: a translational regulatory switch modulated by G-Quadruplexes
The Fragile X Mental Retardation Protein (FMRP) is an RNA binding protein that regulates translation and is required for normal cognition. FMRP upregulates and downregulates the activity of microRNA (miRNA)-mediated silencing in the 3′ UTR of a subset of mRNAs through its interaction with RNA helica...
Autores principales: | Kenny, Phillip J, Kim, Miri, Skariah, Geena, Nielsen, Joshua, Lannom, Monica C, Ceman, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145700/ https://www.ncbi.nlm.nih.gov/pubmed/31740951 http://dx.doi.org/10.1093/nar/gkz1092 |
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