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An in vitro single-molecule assay for eukaryotic cap-dependent translation initiation kinetics
Eukaryotic mRNAs are predominantly translated via the cap-dependent pathway. Initiation is a rate-limiting step in cap-dependent translation and is the main target of translational control mechanisms. There is a lack of high-resolution techniques for characterizing the cap-dependent initiation kinet...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145701/ https://www.ncbi.nlm.nih.gov/pubmed/31722415 http://dx.doi.org/10.1093/nar/gkz1066 |