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An in vitro single-molecule assay for eukaryotic cap-dependent translation initiation kinetics

Eukaryotic mRNAs are predominantly translated via the cap-dependent pathway. Initiation is a rate-limiting step in cap-dependent translation and is the main target of translational control mechanisms. There is a lack of high-resolution techniques for characterizing the cap-dependent initiation kinet...

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Detalles Bibliográficos
Autores principales: Wang, Hongyun, Sun, Lexi, Gaba, Anthony, Qu, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145701/
https://www.ncbi.nlm.nih.gov/pubmed/31722415
http://dx.doi.org/10.1093/nar/gkz1066