A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin

Escherichia coli replication initiator protein DnaA binds ATP with high affinity but the amount of ATP required to initiate replication greatly exceeds the amount required for binding. Previously, we showed that ATP-DnaA, not ADP-DnaA, undergoes a conformational change at the higher nucleotide conce...

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Detalles Bibliográficos
Autores principales: Saxena, Rahul, Stanley, Christopher B, Kumar, Pankaj, Cuneo, Matthew J, Patil, Digvijay, Jha, Jyoti, Weiss, Kevin L, Chattoraj, Dhruba K, Crooke, Elliott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145717/
https://www.ncbi.nlm.nih.gov/pubmed/31665475
http://dx.doi.org/10.1093/nar/gkz939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145717/
https://www.ncbi.nlm.nih.gov/pubmed/31665475
http://dx.doi.org/10.1093/nar/gkz939

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