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The glucose-lowering effects of α-glucosidase inhibitor require a bile acid signal in mice

AIMS/HYPOTHESIS: Bile-acid (BA) signalling is crucial in metabolism homeostasis and has recently been found to mediate the therapeutic effects of glucose-lowering treatments, including α-glucosidase inhibitor (AGI). However, the underlying mechanisms are yet to be clarified. We hypothesised that BA...

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Detalles Bibliográficos
Autores principales: Qiu, Yixuan, Shen, Linyan, Fu, Lihong, Yang, Jie, Cui, Canqi, Li, Tingting, Li, Xuelin, Fu, Chenyang, Gao, Xianfu, Wang, Weiqing, Ning, Guang, Gu, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145781/
https://www.ncbi.nlm.nih.gov/pubmed/32034442
http://dx.doi.org/10.1007/s00125-020-05095-7