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Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB

NifB is a radical S-adenosyl-L-methionine (SAM) enzyme that is essential for nitrogenase cofactor assembly. Previously, a nitrogen ligand was shown to be involved in coupling a pair of [Fe(4)S(4)] clusters (designated K1 and K2) concomitant with carbide insertion into an [Fe(8)S(9)C] cofactor core (...

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Detalles Bibliográficos
Autores principales: Rettberg, Lee A., Wilcoxen, Jarett, Jasniewski, Andrew J., Lee, Chi Chung, Tanifuji, Kazuki, Hu, Yilin, Britt, R. David, Ribbe, Markus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145814/
https://www.ncbi.nlm.nih.gov/pubmed/32273505
http://dx.doi.org/10.1038/s41467-020-15627-9