Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy

Alternative autophagy is an autophagy-related protein 5 (Atg5)-independent type of macroautophagy. Unc51-like kinase 1 (Ulk1) is an essential initiator not only for Atg5-dependent canonical autophagy but also for alternative autophagy. However, the mechanism as to how Ulk1 differentially regulates b...

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Detalles Bibliográficos
Autores principales: Torii, Satoru, Yamaguchi, Hirofumi, Nakanishi, Akira, Arakawa, Satoko, Honda, Shinya, Moriwaki, Kenta, Nakano, Hiroyasu, Shimizu, Shigeomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145817/
https://www.ncbi.nlm.nih.gov/pubmed/32273498
http://dx.doi.org/10.1038/s41467-020-15577-2