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Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death

Timely sister chromatid separation, promoted by separase, is essential for faithful chromosome segregation. Separase is a member of the CD clan of cysteine proteases, which also includes the pro-apoptotic enzymes known as caspases. We report a role for the C. elegans separase SEP-1, primarily known...

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Detalles Bibliográficos
Autores principales: Jeong, Pan Young, Kumar, Ashish, Joshi, Pradeep M., Rothman, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145830/
https://www.ncbi.nlm.nih.gov/pubmed/32273538
http://dx.doi.org/10.1038/s41598-020-63081-w