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Hypoxia imaging and theranostic potential of [(64)Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms

BACKGROUND: Tumor hypoxia (low tissue oxygenation) is an adverse condition of the solid tumor environment, associated with malignant progression, radiotherapy resistance, and poor prognosis. One method to detect tumor hypoxia is by positron emission tomography (PET) with the tracer [(64)Cu][Cu-diace...

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Detalles Bibliográficos
Autores principales: Liu, Tengzhi, Karlsen, Morten, Karlberg, Anna Maria, Redalen, Kathrine Røe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145880/
https://www.ncbi.nlm.nih.gov/pubmed/32274601
http://dx.doi.org/10.1186/s13550-020-00621-5