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Targeting Rho GTPase Signaling Networks in Cancer

As key regulators of cytoskeletal dynamics, Rho GTPases coordinate a wide range of cellular processes, including cell polarity, cell migration, and cell cycle progression. The adoption of a pro-migratory phenotype enables cancer cells to invade the stroma surrounding the primary tumor and move towar...

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Detalles Bibliográficos
Autores principales: Clayton, Natasha S., Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145979/
https://www.ncbi.nlm.nih.gov/pubmed/32309283
http://dx.doi.org/10.3389/fcell.2020.00222