Competition Between Phenothiazines and BH3 Peptide for the Binding Site of the Antiapoptotic BCL-2 Protein

The study of proteins and mechanisms involved in the apoptosis and new knowledge about cancer's biology are essential for planning new drugs. Tumor cells develop several strategies to gain proliferative advantages, including molecular alterations to evade from apoptosis. Failures in apoptosis c...

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Detalles Bibliográficos
Autores principales: do Carmo, Aline Lagoeiro, Bettanin, Fernanda, Oliveira Almeida, Michell, Pantaleão, Simone Queiroz, Rodrigues, Tiago, Homem-de-Mello, Paula, Honorio, Kathia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145989/
https://www.ncbi.nlm.nih.gov/pubmed/32309275
http://dx.doi.org/10.3389/fchem.2020.00235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145989/
https://www.ncbi.nlm.nih.gov/pubmed/32309275
http://dx.doi.org/10.3389/fchem.2020.00235

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