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Competition Between Phenothiazines and BH3 Peptide for the Binding Site of the Antiapoptotic BCL-2 Protein
The study of proteins and mechanisms involved in the apoptosis and new knowledge about cancer's biology are essential for planning new drugs. Tumor cells develop several strategies to gain proliferative advantages, including molecular alterations to evade from apoptosis. Failures in apoptosis c...
Autores principales: | do Carmo, Aline Lagoeiro, Bettanin, Fernanda, Oliveira Almeida, Michell, Pantaleão, Simone Queiroz, Rodrigues, Tiago, Homem-de-Mello, Paula, Honorio, Kathia Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145989/ https://www.ncbi.nlm.nih.gov/pubmed/32309275 http://dx.doi.org/10.3389/fchem.2020.00235 |
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