CRISPR/Cas9-Mediated Foxp1 Silencing Restores Immune Surveillance in an Immunocompetent A20 Lymphoma Model

The interaction of lymphoma cells with their microenvironment has an important role in disease pathogenesis and is being actively pursued therapeutically using immunomodulatory drugs, including immune checkpoint inhibitors. Diffuse large B-cell lymphoma (DLBCL) is an aggressive high-grade disease th...

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Detalles Bibliográficos
Autores principales: Felce, Suet Ling, Anderson, Amanda P., Maguire, Shaun, Gascoyne, Duncan M., Armstrong, Richard N., Wong, Kah Keng, Li, Demin, Banham, Alison H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145990/
https://www.ncbi.nlm.nih.gov/pubmed/32309216
http://dx.doi.org/10.3389/fonc.2020.00448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145990/
https://www.ncbi.nlm.nih.gov/pubmed/32309216
http://dx.doi.org/10.3389/fonc.2020.00448

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