Ibudilast, a Phosphodiesterase-4 Inhibitor, Ameliorates Acute Respiratory Distress Syndrome in Neonatal Mice by Alleviating Inflammation and Apoptosis

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a sudden and serious disease with increasing morbidity and mortality rates. Phosphodiesterase 4 (PDE4) is a novel target for inflammatory disease, and ibudilast (IBU), a PDE4 inhibitor, inhibits inflammatory response. Our study investigated t...

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Detalles Bibliográficos
Autores principales: Yang, Dongjie, Yang, Yihan, Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146065/
https://www.ncbi.nlm.nih.gov/pubmed/32231178
http://dx.doi.org/10.12659/MSM.922281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146065/
https://www.ncbi.nlm.nih.gov/pubmed/32231178
http://dx.doi.org/10.12659/MSM.922281

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