Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways

BACKGROUND: Aseptic prosthetic loosening is one of the main factors causing poor prognosis of limb function after joint replacement and requires troublesome revisional surgery. It is featured by wear particle-induced periprosthetic osteolysis mediated by excessive osteoclasts activated in inflammato...

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Detalles Bibliográficos
Autores principales: Hu, Xuantao, Yin, Ziqing, Chen, Xia, Jiang, Guangyao, Yang, Daishui, Cao, Ziqin, Li, Shuai, Liu, Zicheng, Peng, Dan, Dou, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146087/
https://www.ncbi.nlm.nih.gov/pubmed/32317967
http://dx.doi.org/10.3389/fphar.2020.00385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146087/
https://www.ncbi.nlm.nih.gov/pubmed/32317967
http://dx.doi.org/10.3389/fphar.2020.00385

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