Microwave Assisted Synthesis of 4-Phenylquinazolin-2(1H)-one Derivatives that Inhibit Vasopressor Tonus in Rat Thoracic Aorta

Quinazolinones have pharmacological effects on vascular reactivity through different mechanisms. We synthesized 4-phenylquinazolin-2(1H)-one derivatives under microwave irradiation and tested them on the rat thoracic aorta. The prepared compounds 2a–2f were obtained in about 1 h with suitable yields...

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Detalles Bibliográficos
Autores principales: Teixeira, Rafaela, Menengat, Talita, Andrade, Gabriel, Cotrim, Bruno, Ponte, Cristiano, Santos, Wilson C., Resende, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146288/
https://www.ncbi.nlm.nih.gov/pubmed/32213966
http://dx.doi.org/10.3390/molecules25061467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146288/
https://www.ncbi.nlm.nih.gov/pubmed/32213966
http://dx.doi.org/10.3390/molecules25061467

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