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Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products

There is interest in incorporating nanoemulsions into certain foods and beverages, including dips, dressings, drinks, spreads, and sauces, due to their potentially beneficial attributes. In particular, excipient nanoemulsions can enhance the bioavailability of nutraceuticals in fruit- and vegetable-...

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Autores principales: Zhang, Ruojie, Zhang, Zipei, Li, Ruyi, Tan, Yunbing, Lv, Shanshan, McClements, David Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146406/
https://www.ncbi.nlm.nih.gov/pubmed/32213953
http://dx.doi.org/10.3390/molecules25061466
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author Zhang, Ruojie
Zhang, Zipei
Li, Ruyi
Tan, Yunbing
Lv, Shanshan
McClements, David Julian
author_facet Zhang, Ruojie
Zhang, Zipei
Li, Ruyi
Tan, Yunbing
Lv, Shanshan
McClements, David Julian
author_sort Zhang, Ruojie
collection PubMed
description There is interest in incorporating nanoemulsions into certain foods and beverages, including dips, dressings, drinks, spreads, and sauces, due to their potentially beneficial attributes. In particular, excipient nanoemulsions can enhance the bioavailability of nutraceuticals in fruit- and vegetable-containing products consumed with them. There is, however, potential for them to also raise the bioavailability of undesirable substances found in these products, such as pesticides. In this research, we studied the impact of excipient nanoemulsions on the bioaccessibility of pesticide-treated tomatoes. We hypothesized that the propensity for nanoemulsions to raise pesticide bioaccessibility would depend on the polarity of the pesticide molecules. Bendiocarb, parathion, and chlorpyrifos were therefore selected because they have Log P values of 1.7, 3.8, and 5.3, respectively. Nanoemulsions with different oil contents (0%, 4%, and 8%) were fabricated to study their impact on pesticide uptake. In the absence of oil, the bioaccessibility increased with increasing pesticide polarity (decreasing Log P): bendiocarb (92.9%) > parathion (16.4%) > chlorpyrifos (2.8%). Bendiocarb bioaccessibility did not depend on the oil content of the nanoemulsions, which was attributed to its relatively high water-solubility. Conversely, the bioaccessibility of the more hydrophobic pesticides (parathion and chlorpyrifos) increased with increasing oil content. For instance, for chlorpyrifos, the bioaccessibility was 2.8%, 47.0%, and 70.7% at 0%, 4%, and 8% oil content, respectively. Our findings have repercussions for the utilization of nanoemulsions as excipient foods in products that may have high levels of undesirable non-polar substances, such as pesticides.
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spelling pubmed-71464062020-04-15 Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products Zhang, Ruojie Zhang, Zipei Li, Ruyi Tan, Yunbing Lv, Shanshan McClements, David Julian Molecules Article There is interest in incorporating nanoemulsions into certain foods and beverages, including dips, dressings, drinks, spreads, and sauces, due to their potentially beneficial attributes. In particular, excipient nanoemulsions can enhance the bioavailability of nutraceuticals in fruit- and vegetable-containing products consumed with them. There is, however, potential for them to also raise the bioavailability of undesirable substances found in these products, such as pesticides. In this research, we studied the impact of excipient nanoemulsions on the bioaccessibility of pesticide-treated tomatoes. We hypothesized that the propensity for nanoemulsions to raise pesticide bioaccessibility would depend on the polarity of the pesticide molecules. Bendiocarb, parathion, and chlorpyrifos were therefore selected because they have Log P values of 1.7, 3.8, and 5.3, respectively. Nanoemulsions with different oil contents (0%, 4%, and 8%) were fabricated to study their impact on pesticide uptake. In the absence of oil, the bioaccessibility increased with increasing pesticide polarity (decreasing Log P): bendiocarb (92.9%) > parathion (16.4%) > chlorpyrifos (2.8%). Bendiocarb bioaccessibility did not depend on the oil content of the nanoemulsions, which was attributed to its relatively high water-solubility. Conversely, the bioaccessibility of the more hydrophobic pesticides (parathion and chlorpyrifos) increased with increasing oil content. For instance, for chlorpyrifos, the bioaccessibility was 2.8%, 47.0%, and 70.7% at 0%, 4%, and 8% oil content, respectively. Our findings have repercussions for the utilization of nanoemulsions as excipient foods in products that may have high levels of undesirable non-polar substances, such as pesticides. MDPI 2020-03-24 /pmc/articles/PMC7146406/ /pubmed/32213953 http://dx.doi.org/10.3390/molecules25061466 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Ruojie
Zhang, Zipei
Li, Ruyi
Tan, Yunbing
Lv, Shanshan
McClements, David Julian
Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title_full Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title_fullStr Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title_full_unstemmed Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title_short Impact of Pesticide Type and Emulsion Fat Content on the Bioaccessibility of Pesticides in Natural Products
title_sort impact of pesticide type and emulsion fat content on the bioaccessibility of pesticides in natural products
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146406/
https://www.ncbi.nlm.nih.gov/pubmed/32213953
http://dx.doi.org/10.3390/molecules25061466
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