Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate

Infections caused by bacteria resistant to antibiotics are an increasing problem. Multivalent antibiotics could be a solution. In the present study, a covalent conjugate between Ciprofloxacin and a G0-PAMAM dendrimer has been synthesized and tested against clinically relevant Gram-positive and Gram-...

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Detalles Bibliográficos
Autores principales: Svenningsen, Søren Wedel, Frederiksen, Rikki Franklin, Counil, Claire, Ficker, Mario, Leisner, Jørgen J., Christensen, Jørn Bolstad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146445/
https://www.ncbi.nlm.nih.gov/pubmed/32197523
http://dx.doi.org/10.3390/molecules25061389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146445/
https://www.ncbi.nlm.nih.gov/pubmed/32197523
http://dx.doi.org/10.3390/molecules25061389

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