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Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate
Infections caused by bacteria resistant to antibiotics are an increasing problem. Multivalent antibiotics could be a solution. In the present study, a covalent conjugate between Ciprofloxacin and a G0-PAMAM dendrimer has been synthesized and tested against clinically relevant Gram-positive and Gram-...
Autores principales: | Svenningsen, Søren Wedel, Frederiksen, Rikki Franklin, Counil, Claire, Ficker, Mario, Leisner, Jørgen J., Christensen, Jørn Bolstad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146445/ https://www.ncbi.nlm.nih.gov/pubmed/32197523 http://dx.doi.org/10.3390/molecules25061389 |
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