The Impact of Acute Ingestion of a Ketone Monoester Drink on LPS-Stimulated NLRP3 Activation in Humans with Obesity

Activation of the NOD-like receptor pyrin-domain containing 3 (NLRP3) inflammasome is associated with chronic low-grade inflammation in metabolic diseases such as obesity. Mechanistic studies have shown that β-hydroxybutyrate (OHB) attenuates activation of NLRP3, but human data are limited. In a ran...

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Detalles Bibliográficos
Autores principales: Neudorf, Helena, Myette-Côté, Étienne, P. Little, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146505/
https://www.ncbi.nlm.nih.gov/pubmed/32209983
http://dx.doi.org/10.3390/nu12030854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146505/
https://www.ncbi.nlm.nih.gov/pubmed/32209983
http://dx.doi.org/10.3390/nu12030854

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