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Inflammation-mediated generation and inflammatory potential of human placental cell-free fetal DNA

INTRODUCTION: Circulating DNA can be pro-inflammatory when detected by leukocytes via toll-like receptor 9 (TLR9). Cell-free fetal DNA (cff-DNA) of placental origin, circulates in pregnancy, and increased concentrations are seen in conditions associated with placental and maternal inflammation such...

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Detalles Bibliográficos
Autores principales: van Boeckel, Sara R., Macpherson, Heather, Norman, Jane E., Davidson, Donald J., Stock, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146537/
https://www.ncbi.nlm.nih.gov/pubmed/32250739
http://dx.doi.org/10.1016/j.placenta.2020.02.016