Cargando…

Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation

BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in the select impairment of spatial learning and memory. Exam...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Rossi, Pierre, Nomura, Toshihiro, Andrew, Robert J., Masse, Nicolas Y., Sampathkumar, Vandana, Musial, Timothy F., Sudwarts, Ari, Recupero, Aleksandra J., Le Metayer, Thomas, Hansen, Mitchell T., Shim, Ha-Na, Krause, Sofia V., Freedman, David J., Bindokas, Vytas P., Kasthuri, Narayanan, Nicholson, Daniel A., Contractor, Anis, Thinakaran, Gopal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146643/ https://www.ncbi.nlm.nih.gov/pubmed/32160554 http://dx.doi.org/10.1016/j.celrep.2020.02.026

Ejemplares similares

Alzheimer’s genes in microglia: a risk worth investigating
por: Sudwarts, Ari, et al.
Publicado: (2023)

Dynamic Control of Neurotransmitter Release by Presynaptic Potential
por: Zbili, Mickael, et al.
Publicado: (2016)

Neurotransmitter Release Site Replenishment and Presynaptic Plasticity
por: Mochida, Sumiko
Publicado: (2020)

BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia
por: Sudwarts, Ari, et al.
Publicado: (2022)

Rapid active zone remodeling consolidates presynaptic potentiation
por: Böhme, Mathias A., et al.
Publicado: (2019)

A Glutamate Homeostat Controls the Presynaptic Inhibition of Neurotransmitter Release
por: Li, Xiling, et al.
Publicado: (2018)

Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton
por: Bielecki, Andrzej, et al.
Publicado: (2020)

Neurotransmitter release regulated by a MALS–liprin-α presynaptic complex
por: Olsen, Olav, et al.
Publicado: (2005)

Presynaptic mechanisms underlying GABA(B)-receptor-mediated inhibition of spontaneous neurotransmitter release
por: Alten, Baris, et al.
Publicado: (2022)

Early consolidation of development and physiology of an identified presynaptic nerve terminal
por: Laviolette, Matthew, et al.
Publicado: (2013)

Muscle Dystroglycan Organizes the Postsynapse and Regulates Presynaptic Neurotransmitter Release at the Drosophila Neuromuscular Junction
por: Bogdanik, Laurent, et al.
Publicado: (2008)

Experience-dependent regulation of presynaptic NMDARs enhances neurotransmitter release at neocortical synapses
por: Urban-Ciecko, Joanna, et al.
Publicado: (2015)

PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses
por: Han, Kyung Ah, et al.
Publicado: (2020)

Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release
por: Ahmad-Annuar, Azlina, et al.
Publicado: (2006)

Effect of spatial arrangement of presynaptic calcium channels on the calcium current cooperativity of neurotransmitter release
por: Matveev, Victor, et al.
Publicado: (2011)

Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels
por: Medrihan, Lucian, et al.
Publicado: (2013)

New Insights Into Interactions of Presynaptic Calcium Channel Subtypes and SNARE Proteins in Neurotransmitter Release
por: He, Rongfang, et al.
Publicado: (2018)

Layer 5 of cortex innervates the thalamic reticular nucleus in mice
por: Carroll, Briana J., et al.
Publicado: (2022)

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease
por: Sadleir, Katherine R., et al.
Publicado: (2016)

Associative learning drives longitudinally graded presynaptic plasticity of neurotransmitter release along axonal compartments
por: Stahl, Aaron, et al.
Publicado: (2022)

Influence of the bin to bin and inside bin correlations on measured quantities
por: Perevoztchikov, V, et al.
Publicado: (1999)

Influence of the bin-to-bin and inside bin correlations on measured quantities
por: Perevozchikov, V, et al.
Publicado: (2000)

PhyBin: binning trees by topology
por: Newton, Ryan R., et al.
Publicado: (2013)

Isochronic development of cortical synapses in primates and mice
por: Wildenberg, Gregg, et al.
Publicado: (2023)

Protocol for refining metagenomic binning with BinSPreader
por: Ochkalova, Sofia, et al.
Publicado: (2023)

Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse
por: Richardson, Amy, et al.
Publicado: (2022)

LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons
por: Kwon, Seok-Kyu, et al.
Publicado: (2016)

Improved deconvolution of very weak confocal signals
por: Day, Kasey J., et al.
Publicado: (2017)

BinSPreader: Refine binning results for fuller MAG reconstruction
por: Tolstoganov, Ivan, et al.
Publicado: (2022)

Correction: LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons
por: Kwon, Seok-Kyu, et al.
Publicado: (2018)

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C(1)C(2)BMUN
por: Xu, Junjie, et al.
Publicado: (2017)

C. elegans Clarinet/CLA-1 recruits RIMB-1/RIM-binding protein and UNC-13 to orchestrate presynaptic neurotransmitter release
por: Krout, Mia, et al.
Publicado: (2023)

The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
por: Kandalepas, Patty C., et al.
Publicado: (2013)

Improving metagenomic binning results with overlapped bins using assembly graphs
por: Mallawaarachchi, Vijini G., et al.
Publicado: (2021)

Erratum to: The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
por: Kandalepas, Patty C., et al.
Publicado: (2013)

A pedagogical exercise in binning and resolution
por: Leitner, J, et al.
Publicado: (1967)

Cinder-Bin and Sifter
Publicado: (1892)

Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts
por: De Rossi, Pierre, et al.
Publicado: (2016)

Waste level detection and HMM based collection scheduling of multiple bins
por: Aziz, Fayeem, et al.
Publicado: (2018)

Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease
por: Gong, Ping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0mli396nl4u9224kmq01smlmti