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A Dinuclear Ruthenium(II) Complex Excited by Near-Infrared Light through Two-Photon Absorption Induces Phototoxicity Deep within Hypoxic Regions of Melanoma Cancer Spheroids
[Image: see text] The dinuclear photo-oxidizing Ru(II) complex [{Ru(TAP(2))}(2)(tpphz)](4+) (TAP = 1,4,5,8- tetraazaphenanthrene, tpphz = tetrapyrido[3,2-a:2′,3′-c:3″,2′′-h:2‴,3′′′-j]phenazine), 1(4+), is readily taken up by live cells localizing in mitochondria and nuclei. In this study, the two-ph...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146853/ https://www.ncbi.nlm.nih.gov/pubmed/32065521 http://dx.doi.org/10.1021/jacs.9b11313 |