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Design of a Functionalized Metal–Organic Framework System for Enhanced Targeted Delivery to Mitochondria

[Image: see text] Mitochondria play a key role in oncogenesis and constitute one of the most important targets for cancer treatments. Although the most effective way to deliver drugs to mitochondria is by covalently linking them to a lipophilic cation, the in vivo delivery of free drugs still consti...

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Detalles Bibliográficos
Autores principales: Haddad, Salame, Abánades Lázaro, Isabel, Fantham, Marcus, Mishra, Ajay, Silvestre-Albero, Joaquin, Osterrieth, Johannes W. M., Kaminski Schierle, Gabriele S., Kaminski, Clemens F., Forgan, Ross S., Fairen-Jimenez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146860/
https://www.ncbi.nlm.nih.gov/pubmed/32182066
http://dx.doi.org/10.1021/jacs.0c00188