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Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells

[Image: see text] The loss of insulin-producing β-cells is the central pathological event in type 1 and 2 diabetes, which has led to efforts to identify molecules to promote β-cell proliferation, protection, and imaging. However, the lack of β-cell specificity of these molecules jeopardizes their th...

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Detalles Bibliográficos
Autores principales: Lee, Miseon, Maji, Basudeb, Manna, Debasish, Kahraman, Sevim, Elgamal, Ruth M., Small, Jonnell, Kokkonda, Praveen, Vetere, Amedeo, Goldberg, Jacob M., Lippard, Stephen J., Kulkarni, Rohit N., Wagner, Bridget K., Choudhary, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146867/
https://www.ncbi.nlm.nih.gov/pubmed/32175731
http://dx.doi.org/10.1021/jacs.0c00099