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VanZ Reduces the Binding of Lipoglycopeptide Antibiotics to Staphylococcus aureus and Streptococcus pneumoniae Cells

vanZ, a member of the VanA glycopeptide resistance gene cluster, confers resistance to lipoglycopeptide antibiotics independent of cell wall precursor modification by the vanHAX genes. Orthologs of vanZ are present in the genomes of many clinically relevant bacteria, including Enterococcus faecium a...

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Detalles Bibliográficos
Autores principales: Vimberg, Vladimir, Zieglerová, Leona, Buriánková, Karolína, Branny, Pavel, Balíková Novotná, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146870/
https://www.ncbi.nlm.nih.gov/pubmed/32318043
http://dx.doi.org/10.3389/fmicb.2020.00566