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Long non-coding RNA GAS5 accelerates oxidative stress in melanoma cells by rescuing EZH2-mediated CDKN1C downregulation

BACKGROUND: The significance of long non-coding RNAs (lncRNAs) in mediating oxidative stress of cancers has been implicated recently. This study proposed a potential therapeutic target lncRNA growth arrest-specific transcript 5 (GAS5) for melanoma, due to its crucial role in oxidative stress and apo...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Yan, Zeqiang, Hu, Fen, Wei, Wei, Yang, Chao, Sun, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146881/
https://www.ncbi.nlm.nih.gov/pubmed/32308561
http://dx.doi.org/10.1186/s12935-020-01167-1