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Bone marrow mesenchymal stem cell-derived exosomal microRNA-124-3p attenuates neurological damage in spinal cord ischemia-reperfusion injury by downregulating Ern1 and promoting M2 macrophage polarization

BACKGROUND: Spinal cord ischemia-reperfusion injury (SCIRI) often leads to neurological damage and mortality. In this regard, understanding the pathology of SCIRI and preventing its development are of great clinic value. METHODS: Herein, we analyzed the role of bone marrow mesenchymal stem cell (BMM...

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Detalles Bibliográficos
Autores principales: Li, Ran, Zhao, Kunchi, Ruan, Qing, Meng, Chunyang, Yin, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146970/
https://www.ncbi.nlm.nih.gov/pubmed/32272965
http://dx.doi.org/10.1186/s13075-020-2146-x