Formononetin inhibits tumor growth by suppression of EGFR-Akt-Mcl-1 axis in non-small cell lung cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) activating mutations play crucial roles in the tumorigenesis of human non-small cell lung cancer (NSCLC). The mechanism regarding how EGFR signaling regulates myeloid cell leukemia sequence 1 (Mcl-1) protein stability and ubiquitination remains und...

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Detalles Bibliográficos
Autores principales: Yu, Xinyou, Gao, Feng, Li, Wei, Zhou, Li, Liu, Wenbin, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146989/
https://www.ncbi.nlm.nih.gov/pubmed/32276600
http://dx.doi.org/10.1186/s13046-020-01566-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146989/
https://www.ncbi.nlm.nih.gov/pubmed/32276600
http://dx.doi.org/10.1186/s13046-020-01566-2

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