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Toxo: a library for calculating penetrance tables of high-order epistasis models

BACKGROUND: Epistasis is defined as the interaction between different genes when expressing a specific phenotype. The most common way to characterize an epistatic relationship is using a penetrance table, which contains the probability of expressing the phenotype under study given a particular allel...

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Detalles Bibliográficos
Autores principales: Ponte-Fernández, Christian, González-Domínguez, Jorge, Carvajal-Rodríguez, Antonio, Martín, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147067/
https://www.ncbi.nlm.nih.gov/pubmed/32272874
http://dx.doi.org/10.1186/s12859-020-3456-3